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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RCC1 All Species: 25.45
Human Site: S29 Identified Species: 46.67
UniProt: P18754 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18754 NP_001041659.1 421 44969 S29 K V K V S H R S H S T E P G L
Chimpanzee Pan troglodytes XP_001152659 421 44920 S29 K V K V S H R S H S T E P G L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544458 630 67681 S238 K V K V S H R S H S T E P G I
Cat Felis silvestris
Mouse Mus musculus Q8VE37 421 44912 S29 K V K V S H R S H N T E P G L
Rat Rattus norvegicus NP_001121661 421 45093 S29 K V K V S H R S H N T E P G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_427366 194 21051
Frog Xenopus laevis P25183 424 45052 S35 L P I V T H P S H G T V G G Q
Zebra Danio Brachydanio rerio Q6NYE2 495 54133 K48 E N T K K P G K P A A K A G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25171 547 58832 A29 K A K R A R I A F H L E L P K
Honey Bee Apis mellifera XP_394158 439 46956 E37 K Q I R K K Q E L V V K P D L
Nematode Worm Caenorhab. elegans Q18211 569 61466 E59 Q V E L A A M E T E A S D S I
Sea Urchin Strong. purpuratus XP_001191815 424 45249 S32 K V K V S H W S H Q S K P G F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P21827 482 52995 Y40 Q E D Y K H M Y L S V Q P L D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 64.7 N.A. 93.8 93.3 N.A. N.A. 37 75.9 22.2 N.A. 29 45.5 29.5 52.8
Protein Similarity: 100 99.7 N.A. 65.8 N.A. 96.9 96.6 N.A. N.A. 42 85.6 40 N.A. 43.6 63 42.5 70.7
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. N.A. 0 40 13.3 N.A. 20 20 6.6 66.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 0 46.6 33.3 N.A. 33.3 33.3 40 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 16 8 0 8 0 8 16 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 0 0 0 8 8 8 % D
% Glu: 8 8 8 0 0 0 0 16 0 8 0 47 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 0 8 0 0 8 0 0 8 62 0 % G
% His: 0 0 0 0 0 62 0 0 54 8 0 0 0 0 0 % H
% Ile: 0 0 16 0 0 0 8 0 0 0 0 0 0 0 16 % I
% Lys: 62 0 54 8 24 8 0 8 0 0 0 24 0 0 8 % K
% Leu: 8 0 0 8 0 0 0 0 16 0 8 0 8 8 47 % L
% Met: 0 0 0 0 0 0 16 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 16 0 0 0 0 0 % N
% Pro: 0 8 0 0 0 8 8 0 8 0 0 0 62 8 0 % P
% Gln: 16 8 0 0 0 0 8 0 0 8 0 8 0 0 8 % Q
% Arg: 0 0 0 16 0 8 39 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 47 0 0 54 0 31 8 8 0 8 0 % S
% Thr: 0 0 8 0 8 0 0 0 8 0 47 0 0 0 0 % T
% Val: 0 54 0 54 0 0 0 0 0 8 16 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _